不对称的总合成和DAT的结构修订2,这是来自Mycobacterium tuberculosis的抗原性糖脂

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Zonghao Lin1, Jeya Prathap Kaniraj1, Mira Holzheimer1

  • 1Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

Angewandte Chemie (International ed. in English)
|March 8, 2024
PubMed
概括

研究人员确定了二甲基三糖2 (DAT2) 的正确结构,这是Mycobacterium tuberculosis的一个关键抗原. DAT2的自然形式显示出免疫受体的最强激活,这表明其对诊断和疫苗的潜力.

关键词:
抗原性是一种抗原性.二氧乙基三糖二氧乙基三糖.有机合成有机合成立体化学是一种立体化学.结构性调整是结构性调整.

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