导航双出口右心室表现的频谱:基于亚型的当代队列的结果
Aydın Öcal1, Oya Demirci1, Özge Kahramanoğlu1
1Department of Perinatology, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Echocardiography (Mount Kisco, N.Y.)
|March 8, 2024
概括
双出口右心室 (DORV) 的预后取决于其亚型和相关异常. 在没有额外的结构或遗传问题的孤立病例中,生存率更高.
科学领域:
- 心脏病学 心脏病学
- 产前诊断 在产前诊断
- 遗传性心脏缺陷 遗传性心脏缺陷
背景情况:
- 双出口右心室 (DORV) 是一种复杂的先天性心脏缺陷.
- 准确的产前诊断对于评估预后和规划管理至关重要.
- 了解亚型特定的结果对于临床决策至关重要.
研究的目的:
- 调查双出口右心室 (DORV) 的产前和产后预后.
- 分析基于在产前诊断的不同DORV亚型的结果.
- 为了将相关的异常与患者的生存和治疗策略相关联.
主要方法:
- 通过产前超声波 (2014-2022) 诊断的DORV病例的回顾性图表审查.
- 数据收集包括母体特征,胎儿心声学特征 (DORV亚型) 和怀孕/新生儿结果 (TOP,IUD,NND,IND,生存率).
- 根据DORV亚型分层对结果的分析以及额外的心脏或心脏外异常的存在.
主要成果:
- 分析了99例产前确诊的DORV病例;97%的活产胎儿得到了准确的产前诊断.
- 其中DORV亚型包括:异质毒性 (35.3%),大动脉转移 (TGA) (32.3%),落 (19.1%) 和心室隔膜缺陷 (VSD) (11.1%).
- 观察到高率的相关异常 (87%心脏,54%心脏外). 生产后的存活率为57.3%,增加到术后修复后的81.2%,在孤立的情况下有更好的结果.
结论:
- DORV的预后受到其解剖学亚型的显著影响.
- 相关的结构和遗传异常严重影响生存率.
- 没有额外异常的孤立DORV病例显示出更好的生存率,强调了综合遗传和心脏评估的重要性.
相关概念视频
Pulmonary Hypertension: Classification and Pathogenesis
180
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
There are various classifications for PH, each relating to different underlying causes and also...
180
Pathophysiology of Heart Failure
1.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.6K
Imaging Studies for Cardiovascular System II:Types of Echocardiography
267
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
267
Cardiovascular System Abnormal Findings II: Auscultation
148
Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
Abnormal Heart Sounds
Gallops:
148


