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Updated: Jul 1, 2025

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
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为了降低胆固醇,利用RNA干扰:Inclisiran的长沙到床边的故事

Michael J Wilkinson1, Archna Bajaj2, Margaret E Brousseau3

  • 1Division of Cardiovascular Medicine, Department of Medicine Cardiovascular Institute, University of California San Diego San Diego CA USA.

Journal of the American Heart Association
|March 8, 2024
PubMed
概括

作为一种RNA干扰疗法,Inclisiran可显著降低低密度脂蛋白胆固醇 (LDL-C) 的50%,每年服用两次. 这为动脉样硬化心血管疾病患者提供了新的选择,这些患者无法达到LDL-C的目标.

关键词:
动脉样硬化心血管疾病这里是inclisiran的意思.低密度脂蛋白胆固醇是低密度脂蛋白胆固醇的一种.蛋白转化酶亚提利辛/凯类型9小小的干扰RNA可以干扰RNA.

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