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抗体/MHC-I复合体的实验结构揭示了计算预测忽略的表皮层的细节

Lisa F Boyd1, Jiansheng Jiang1, Javeed Ahmad1

  • 1Molecular Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

Journal of immunology (Baltimore, Md. : 1950)
|March 8, 2024
PubMed
概括

针对MHC I类 (MHC-I) 的单克隆抗体 (mAbs) 对免疫学至关重要. 确定mAb结合/MHC-I复合物的结构揭示了结合点和计算建模的局限性.

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