概括
骨盆排气后的空骨盆综合征 (EPS) 是一个重要的并发症. 这项研究将EPS定义为一个核心结果集和描述符,以指导未来的研究和改善患者护理.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 妇科瘤学 妇科瘤学
背景情况:
- 空骨盆综合征 (EPS) 是骨盆排泄 (PE) 后的主要致病原因,但缺乏明确的定义.
- 对EPS结果和手术激进性的不一致报告妨碍了对预防策略的理解.
- 对于EPS来说,有必要制定标准化的定义和结果指标.
研究的目的:
- 为EPS建立一个可测量的核心成果集.
- 定义一个核心描述符集,用于与EPS相关的PE的极端性.
- 制定基于共识的EPS书面定义,并探索减缓策略.
主要方法:
- 采用了三阶段的共识方法,包括系统审查,专家会议,患者参与,以及修改的Delphi和名义组技术.
- 德尔菲和共识阶段分别有103个人和119人的国际多学科参与.
- 结果指标,描述符的代改进,以及EPS的书面定义.
主要成果:
- 在七个核心结局方面达成了共识:肠道阻塞,肠管,慢性围鼻,感染的骨盆收集,重建发病率,再干预和生活质量.
- 确定了四个核心描述因素:手术的程度,放射治疗引起的损伤,重建方法和骨盆死亡空间体积变化.
- 对EPS的标准化书面定义达成一致,适用时使用定义的测量仪器.
结论:
- 本研究通过提供基于共识的EPS定义来解决尚未满足的临床和研究需求.
- 建立的核心结果和描述器集将标准化报告,并促进未来对EPS的研究.
- 标准化对于推动了解和管理盆腔挖掘后的EPS至关重要.
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