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与食物相关的生活质量及其预测因素在炎症性肠病中的预测因素
Raquel Oliveira1,2, Viviana Martins3,4, Helena Tavares de Sousa3,4
1Gastroenterology Department, Algarve University Hospital Centre, Estrada do Poço Seco, 8500-338, Portimão, Portugal. raquel.f.oliveira@chua.min-saude.pt.
炎症性肠病 (IBD) 患者经历了与食物相关的生活质量 (FR-QoL) 的显著降低,无论疾病的活性如何. 心理社会因素,如对食物的焦虑和抑郁情绪,进一步损害IBD中的FR-QoL.
科学领域:
- 胃肠病学 胃肠病学
- 生活质量研究 研究 生命质量研究
- 精神病体医学是一种精神病体医学.
背景情况:
- 炎症性肠病 (IBD) 通过饮食限制和限制显著影响日常生活.
- 与食物相关的生活质量 (FR-QoL) 仍然是IBD管理中未得到解决的一个方面.
- 了解影响FR-QoL的因素对于改善患者福祉至关重要.
研究的目的:
- 在IBD患者队列中研究FR-QoL的决定因素.
- 检查疾病活动的客观测量和FR-QoL之间的关系.
- 为了比较IBD患者和对照组之间的FR-QoL.
主要方法:
- 一项涉及成年IBD患者和对照者的横截面病例控制研究.
- 使用匿名问卷评估社会人口统计数据,FR-QoL (FR-QoL-29) 和与健康有关的生活质量 (SIBDQ).
- 使用基于医生的得分 (Harvey-Bradshaw,部分Mayo) 和便calprotectin水平评估的疾病活性.
主要成果:
- 与对照组相比,IBD患者的FR-QoL显著降低,无论疾病的活性如何.
- 活跃疾病与FR-QoL比缓解更差 (p < 0.001).
- FR-QoL与整体生活质量相关 (SIBDQ,r=0.490) 并受到抑郁情绪和与食物有关的焦虑的负面影响.
结论:
- IBD患者在FR-QoL中经历了显著的损伤,独立于疾病类型和活性.
- 心理社会因素,包括情感状态和对食物的恐惧,是导致FR-QoL降低的重要因素.
- 一种多学科的方法,包括定制的营养咨询,对于管理IBD的FR-QoL至关重要.
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