描述心肺呼吸能力对左心房大小和功能在一般人群中的影响
Luke Spencer1,2, Leah Wright3, Stephen J Foulkes4
1St Vincent's Institute, Fitzroy, Victoria, Australia.
概括
在健康个体中,较大的左心房 (LA) 尺寸预测了更高的心肺呼吸能力 (CRF),挑战了LA扩大仅作为病理学的观点. 在这个人群中,LA函数并不能显著预测CRF.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 心脏成像 - - 心脏成像
背景情况:
- 左心房 (LA) 尺寸增加和LA功能减少与心力衰竭和心房动有关.
- 前庭改造也与运动训练有关,但健身,LA大小和健身范围内的功能之间的关系尚不清楚.
研究的目的:
- 在表面上健康的个体中,定义心肺健康 (CRF),LA大小和LA功能之间的关系.
- 调查影响CRF的心房因素中的潜在性别差异.
主要方法:
- 在559名健康参与者 (304名男性,255名女性) 的横截面研究中.
- 对LA体积的心声检测,以身体表面积 (LAVi) 和心房变形 (LA应变) 进行索引.
- 心肺运动测试 (CPET) 用于测量峰值氧气消耗 (V·o2峰).
主要成果:
- 多变量回归显示年龄,性别,体重,LAVi显著预测了Vo2峰 (R2 = 0.66).
- 心率储备进一步改善了预测 (R2 = 0.74),但LA菌株参数没有预测V̇o2峰.
- LA结构 (大小) 比LA功能更好地预测CRF.
结论:
- 在心肺健康的背景下,应考虑LA大小.
- 增加LA大小的不良预后关联可能仅限于LA扩大和身体健康低下的个体.
- 一旦考虑LA大小,LA函数将在健康个体中增加CRF的最小预测值.
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