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Updated: Jul 1, 2025

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估计双向因果效应的方法,使用孟德尔随机化,并应用于体重指数和禁食葡萄糖

Jinhao Zou1, Rajesh Talluri1,2, Sanjay Shete1,3

  • 1Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

PloS one
|March 8, 2024
PubMed
概括

新的门德尔随机化 (MR) 方法,BiRatio和BiLIML,准确估计表型之间的双向因果效应. 推采用BiLIML方法,特别是使用软弱的遗传仪器,并发现肥胖和糖尿病之间存在双向联系.

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