囊下鼻巨细胞在血液传播的病毒感染期间最大限度地促进非排水淋巴结中的生殖中心发育

Cynthia C Aguilar1, Anurag Kalia1, Morgan E Brisse1

  • 1Viral Immunity and Pathogenesis Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Science immunology
|March 8, 2024
PubMed
概括

这项研究揭示了淋巴结 (LN) 巨细胞如何捕获血液传播的寨卡病毒 (ZIKV),以启动生殖中心 (GC) 的抗病毒B细胞反应. 它揭示了一条保护的途径,用于激活远离最初感染地点的LNs中的B细胞.

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