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Updated: Jul 1, 2025

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贝雷EP4 - 阴性基底细胞癌:一个不能忘记的免疫表型

Douglas W Murray¹, Robert W Thiel², Mariana A Phillips^1,2

¹Virginia Tech Carilion School of Medicine, Roanoke, VA.

The American Journal of dermatopathology

|March 8, 2024

概括

基础细胞癌 (BCC) 可能是BerEP4阴性,具有挑战性的诊断. 这一案例凸显了需要考虑非典型的BCC呈现,即使是其他癌症的阳性标志物,以避免误诊.

科学领域:

在瘤学瘤学.
免疫组织化学免疫组织化学
皮肤病理学皮肤病理学

背景情况:

基底细胞癌 (BCC) 是全球最常见的癌症,其特点是局部侵入性.
针对CD326 (EpCAM) 的抗体BerEP4,对BCC具有高灵敏度,但对其他癌症具有可变的灵敏度.
正确的诊断至关重要,因为BCC有可能造成局部破坏.

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