静脉鼻支架用于异常性内高血压:一个更新的元分析
Ahmed Y Azzam1, Ali Mortezaei2, Mahmoud M Morsy3
1Montefiore-Einstein Cerebrovascular Research Lab, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA; Faculty of Medicine, October 6 University, Giza, Egypt; Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Journal of the neurological sciences
|March 8, 2024
概括
静脉鼻腔支架 (VSS) 是一种安全有效的治疗方法,可以显著降低血压和改善症状,治疗异常性内高血压 (IIH). 虽然并发症会发生,但VSS对那些对医疗治疗没有反应的患者来说是有前途的.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 干预性放射学 干预性放射学
背景情况:
- 异常性内高血压 (IIH) 影响生育年龄的肥胖女性,导致内血压升高.
- 静脉鼻腔支架 (VSS) 是IIH治疗的一个有争议的外科选择.
研究的目的:
- 系统地审查和对静脉鼻支架 (VSS) 的安全性和疗效进行元分析,对被诊断患有异常性内高血压 (IIH) 的患者进行.
主要方法:
- 根据PRISMA指南进行了系统审查和元分析.
- 来自36项涉及1066名因IIH而接受VSS治疗的患者的研究数据被汇总和分析.
主要成果:
- 在IIH患者中,VSS显著降低了跨静脉梯度压力和脑脊液 (CSF) 开口压力.
- 在耳 (95%),乳头瘤 (89%),视力障碍 (88%) 和头痛 (79%) 中观察到显著的临床改善.
- 结合治疗失败率和并发症率为13.7%,失败率为8.35%,并发症率为5.35%,包括出血和支架血栓形成.
结论:
- 在IIH患者中,VSS证明了对治疗不耐药或视力严重受损的患者的安全性和有效性.
- 需要进一步的研究来确定VSS在IIH管理中的长期结果和安全概况.
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