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Updated: Jul 1, 2025

Visualization of Thalamocortical Axon Branching and Synapse Formation in Organotypic Cocultures
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Visualization of Thalamocortical Axon Branching and Synapse Formation in Organotypic Cocultures

Published on: March 28, 2018

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发展有答案:通过心皮层的器官来解开精神疾病

Eduardo Leyva-Díaz1, Emily S Wilson1, Guillermina López-Bendito1

  • 1Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), San Juan de Alicante, Alicante, Spain.

Cell stem cell
|March 8, 2024
PubMed
概括

来自患者的甲状腺皮质器官揭示了22q11.2微切除如何影响甲状腺发育. 这种精神疾病的遗传原因导致发育中的 thalamus 中显著的转录失调.

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Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

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Author Spotlight: Advancing Genetic Epilepsy Studies with Multi-Electrode Array-Based Long-Term Electrophysiological Monitoring of Human Brain Assembloids

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Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
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