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从抑制剂到增强剂:IL-10在CAR-T细胞治疗中对固体瘤的替代作用

Yuwei Huang1, Haopeng Wang2

  • 1School of Life Science and Technology, ShanghaiTech University, Shanghai, China; Lingang Laboratory, Shanghai 200031, China.

Cell stem cell
|March 8, 2024
PubMed
概括

介质蛋白-10 (IL-10) 重编程化学抗原受体T细胞 (CAR-T),以提高它们对固体瘤的有效性. 这种方法还促进了持久的免疫记忆,挑战了IL-10的传统免疫抑制作用.

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