关于从孕期到怀孕和哺乳期的炎症性肠病管理的最新信息
Ole Haagen Nielsen1, John Mark Gubatan2, Kaija-Leena Kolho3
1Department of Gastroenterology, Medical Section, Herlev Hospital, Copenhagen, Denmark; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Denmark.
控制炎症性肠道疾病对于生殖计划至关重要. 通过药物维持缓解可以优化怀孕的结果,并减少父母和孩子的风险.
科学领域:
- 胃肠病学和生殖医学
- 免疫学与遗传学
背景情况:
- 炎症性肠道疾病 (IBD) 对生殖计划提出了独特的挑战,影响了心理健康,并需要进行手术.
- 遗传因素有助于疾病的传播,如果父母之一患有IBD,后代的风险约为10%,如果父母都患有IBD,风险增加到33%.
研究的目的:
- 提供全面的,以证据为基础的关于治疗炎症性肠病 (IBD) 的指导,以获得成功的妊娠结果.
- 为患者和临床医生提供有关生育因素,怀孕期间疾病活动的风险和安全诊断程序的信息.
主要方法:
- 关于IBD,生育能力,怀孕和管理策略的当前科学文献和临床证据的审查.
- 分析与IBD药物,疾病爆发和怀孕期间手术相关的风险.
主要成果:
- IBD 患者的生育能力与一般人群相比,尽管活跃的疾病或特定的手术史可能会降低其.
- 怀孕期间的疾病爆发增加了风险,包括早产; 通过药物维持缓解是至关重要的.
- 某些诊断程序如柔性内镜,肠道超声波和无加多MRI在妊娠期间被认为是安全的.
结论:
- 最佳的IBD管理,包括在怀孕前实现疾病缓解和继续适当的药物治疗,是确保怀孕结果的关键.
- 有关药物使用的知情决策,平衡治疗风险与疾病活动的危险,对于患有IBD的孕妇至关重要.
更多相关视频
08:50A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
09:01Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
Published on: March 10, 2015
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
