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Updated: Jul 1, 2025

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多策略直角增强和分析阿尔多-基托减少酶的热稳定性

Lingzhi Zhang1, Rui Zhou2, Dekai Liu1

  • 1College of Chemical Engineering, Huaqiao University, Xiamen 361021, Fujian Province, PR China.

International journal of biological macromolecules
|March 8, 2024
PubMed
概括

提高酶的热稳定性对于工业应用至关重要. 这项研究使用蛋白质设计和突变改进了阿尔多基因减小酶 (AKR7-2-1) 的稳定性,显著增加了其化温度和半衰期.

关键词:
阿尔多克氨酸还原酶.计算设计 计算设计蛋白质工程是一种蛋白质工程.理性的设计理性的设计.

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