儿童早期症状和精神病类经历的发展轨迹
Luxia Jia1, Ziqian Wei2, Juan Wang2
1School of Education, Guangzhou University, Guangzhou, China; Vanke School of Public Health, Tsinghua University, Beijing, China; Institute of Healthy China, Tsinghua University, Beijing, China.
Brain research
|March 8, 2024
概括
持久性精神病类似经历 (PLEs) 的儿童面临更高的风险,以后精神病障碍. 心理和行为问题是PLE轨迹的关键预测因素,使早期干预成为可能.
科学领域:
- 儿童和青少年精神病学
- 发展心理学 发展心理学
- 神经科学是一个神经科学.
背景情况:
- 儿童持续性精神病类经历 (PLEs) 与患精神病障碍的风险增加有关.
- 了解PLEs的不同发展轨迹对于早期识别和干预至关重要.
研究的目的:
- 识别早期特征,区分和预测儿童PLE的各种发育轨迹.
- 检查基线心理,行为,认知和神经生物学因素与PLE轨迹之间的关联.
主要方法:
- 利用了来自青少年大脑认知发展 (ABCD) 研究的纵向数据.
- 将参与者分为五个PLEs轨迹组:持久性,缓解性,增长性,缓解性和没有PLEs.
- 采用线性和通用线性混合效应模型来分析基线特征的差异.
主要成果:
- 心理和行为问题 (例如,ADHD,社会,注意力,思维问题) 与所有PLEs群体有关.
- 与缓解组相比,持久性PLE组表现出较高的ADHD/社会/思想问题和自杀行为.
- 较差的认知功能,特定的大脑结构异常 (叶,上边),创伤和较低的收入与一些,但不是所有,与没有PLEs组相比的PLEs组有关.
结论:
- PLEs的发展是一个动态的过程,涉及多个领域的变化.
- 心理和行为问题是PLE出现和持续的重要预测因素.
- 强调对心理和行为问题的评估对于患有精神疾病风险的儿童的早期,精确的干预至关重要.
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