在布鲁加达综合征的负电生理学研究后,使用植入式循环记录器检测心律失常:来自多中心国际注册表的观察
Eusebio García-Izquierdo1, Chiara Scrocco2, Julián Palacios-Rubio3
1Arrhythmia Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.
Heart rhythm
|March 8, 2024
概括
植入式循环记录器 (ILR) 在负电生理学研究 (EPS) 后对布鲁加达综合征 (BrS) 风险分层安全. 这种方法可以检测出显著的节律失常事件,在许多患者中指导治疗.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 医疗器械 医疗器械
背景情况:
- 布鲁加达综合征 (BrS) 的风险分层具有挑战性.
- 在BrS风险分层中,电生理学研究 (EPS) 的实用性得到了讨论.
- 植入式循环记录器 (ILR) 有时在负EPS之后用于BrS风险分层,但其诊断价值尚不清楚.
研究的目的:
- 描述在BrS患者负EPS后使用ILR监测的特点和发现.
- 评估BRS患者的ILR诊断值,这些患者之前的EPS是负的.
主要方法:
- 在ILR植入之前具有负EPS的BrS患者的回顾性国际注册.
- 从荷兰,西班牙和英国的8家转诊医院收集的数据.
- 随访时间中位数为39个月.
主要成果:
- 65名负EPS的BrS患者接受了ILR监测.
- 在随访期间,18名患者 (27.7%) 经历了21次心律失常事件 (AEs);没有死亡.
- 勃拉迪心律不整最常见 (47.6%),其次是心房心律不整 (38.1%);只有3人患有心室心律不整. 副作用导致11名患者 (61.1%) 的治疗变化.
结论:
- 在负EPS之后使用ILR是BrS的安全策略.
- 这种方法证实了EPS在BrS中的心室失常症的高负预测值.
- 在ILR监测中,在很大一部分患者中检测到具有治疗意义的显著副作用.
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