在加拿大阿尔伯塔省的成年人中,COVID-19后的症状:一项观察性调查研究
Xueyi Chen1,2, Colleen Norris3, Tara Whitten1,2
1Alberta Strategy for Patient-Oriented Research Support Unit Data Platform, Edmonton, Alberta, Canada.
BMJ open
|March 8, 2024
概括
COVID-19幸存者报告的症状明显高于一般人群,包括疲劳和神经问题. 这凸显了针对长期COVID患者的有针对性的管理策略的需要.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 长期COVID症状如疲劳和睡眠问题是常见的,但可以与一般人口症状重叠.
- 区分COVID-19特定症状和与大流行有关的压力对于准确的诊断和管理至关重要.
研究的目的:
- 为了比较COVID-19阳性测试的个体报告的症状,与那些测试负面的人进行比较.
- 识别与COVID-19阳性相关的症状和症状报告的风险因素.
主要方法:
- 一项观察性研究涉及加拿大阿尔伯塔省的7623名COVID-19阳性和1520名负性成年居民 (2021年10月至2023年2月).
- 用国际严重急性呼吸道和新兴感染联盟 (ISARIC) 长期跟踪工具改编的调查来评估自我报告的症状.
- 参与者在COVID-19测试后超过28天,索引测试日期在2020年3月至2022年12月之间.
主要成果:
- COVID-19阳性个体报告的症状比负面个体多1.5倍.
- 阳性病例的首要症状包括疲劳 (42%);头痛在负面病例中最常见 (32%).
- COVID-19幸存者在40种症状中经历了31种症状的几率更高,包括嗅觉功能障碍,月经变化和心肺/神经系统问题. 女性性别,中年,土著身份,失业,住院和先前存在的疾病预测了更多的症状.
结论:
- COVID-19幸存者经历了大量和各种各样的持续症状.
- 调查结果支持针对受影响人口不平等的有针对性的管理策略的需要.
- 适当的症状缓解管理对于从急性COVID-19疾病中恢复过来的个人至关重要.
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