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维生素D和代谢表型在腹手术后减肥:一个纵向研究
Suelem Pereira da Cruz1, Sabrina Pereira da Cruz2, Silvia Pereira3
1Center for Research On Micronutrients, Federal University of Rio de Janeiro (NPqM/UFRJ), Rio de Janeiro, 21941-902, Brazil. suelemcruz.med@gmail.com.
Obesity surgery
|March 8, 2024
概括
在减肥手术前,维生素D的充足量和健康的代谢表型可以改善身体脂肪的分布. 然而,维生素D不足和不健康的表型导致手术后更大的减肥.
科学领域:
- 代谢手术 代谢手术
- 营养生物化学 营养生物化学
- 肥胖问题研究研究
背景情况:
- 鲁克斯-en-Y胃绕道 (RYGB) 是一种常见的减肥手术.
- 代谢表型和维生素D状况是肥胖管理的关键因素.
- 了解它们在RYGB前后的相互作用对于优化患者的治疗结果至关重要.
研究的目的:
- 调查手术前维生素D (VD) 度和代谢表型对身体组成和体重减轻的影响.
- 为了评估这些影响,在RYGB手术后6个月.
主要方法:
- 这是一项对30名接受RYGB.治疗的成年患者进行纵向,回顾性研究.
- 参与者在手术前被分为代谢健康的肥胖者 (MHO) 和代谢不健康的肥胖者 (MUHO) 组.
- 使用HPLC-UV.评估体内的变量,体重减轻,以及使用HPLC-UV.使用25(OH) D和1,25(OH) 2D度
主要成果:
- 手术前的静脉动脉充足度和MHO与腰与身高比率 (WHtR) 和身体圆度指数 (BCI) 的降低有关.
- 维生素D不足和MUHO与手术后更高的身体脂肪指数 (BAI) 有关.
- 维生素D不足,即使具有不健康的表型,也可能增加RYGB后的内脏脂肪指数 (VAI).
结论:
- 维生素D的充足度和健康的表型对RYGB后的内脏脂肪减少有积极的影响.
- 在维生素D不足和MUHO表型患者中观察到更大的体重减轻.
- 这表明,在这个小组的腹部外科手术后,体积稀释和代谢效应更明显.
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