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Updated: Jul 1, 2025

Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation
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Published on: November 26, 2014

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由XIST进行的三胞体沉默:翻译前景和挑战

Khusali Gupta1, Jan T Czerminski1,2, Jeanne B Lawrence3,4

  • 1Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA.

Human genetics
|March 8, 2024
PubMed
概括

通过沉默额外的染色体,XIST RNA有可能治疗像唐氏综合征这样的染色体剂量障碍. 进一步的研究可能会导致基于XIST的"染色体疗法"用于遗传疾病.

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