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Updated: Jul 1, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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德克-1通过在喘中通过卡斯帕-11/4介导的巨细胞激增炎症加剧中性粒细胞的炎症

Runjin Cai1,2, Xiaoxiao Gong1,2, Xiaozhao Li3,2

  • 1Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.

Respiratory research
|March 8, 2024
PubMed
概括

德克-1激活通过触发卡斯帕-11/4介导的巨细胞灭和化学激素释放来加剧喘,导致呼吸道炎症增加. 抑制这种途径可以缓解喘模型中的症状.

关键词:
喘 喘 是一种卡斯帕斯-11是一种这是Dectin-1的原始成分.作为一个中性粒细胞.热灭菌的发生.

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