在具有治愈意图的局部治疗后,前列腺癌患者的脏移植:系统性审查
C Rumpff1, V Lieb2,3, B Wullich2,3
1Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany.
World journal of urology
|March 9, 2024
概括
前列腺癌治疗后的移植仍然是不确定的. 由于证据确定性非常低,决定需要与移植专家进行个性化咨询.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植医学 移植医学
背景情况:
- 前列腺癌是男性常见的恶性瘤.
- 脏移植是末期脏疾病的拯救生命的手术.
- 移植后前列腺癌治疗的安全性和有效性尚未得到充分证实.
研究的目的:
- 评估目前关于移植安全性的证据,以治疗意图治疗前列腺癌病史的患者.
- 确定任何关于管理这些患者的既定指南或建议.
主要方法:
- 在多个数据库 (谷歌,MEDLINE,Cochrane图书馆,ICTRP) 进行系统的文献搜索.
- 包括官方标准,临床实践指南和器官移植法律.
- 使用GRADE方法提取数据并评估证据确定性.
主要成果:
- 包括有限数量的参考文献,包括官方标准和回顾性研究.
- 追溯研究的证据确定性被评为非常低.
- 没有发现有前性或正在进行的研究.
结论:
- 对于前列腺癌患者的移植决定,治疗后治疗应该是个性化的.
- 咨询医疗保健专业人员和移植中心对于个性化的等待时间信息至关重要.
- 由于证据不足,无法对前列腺癌治疗后的等待时间做出明确的建议.
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