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Updated: Jul 1, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
09:03

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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关于化学计量驱动的多层优先级的第一份报告,以解决G蛋白结合受体183的氧化醇介导过度表达

Arnab Bhattacharjee1, Supratik Kar2, Probir Kumar Ojha3

  • 1Drug Discovery and Development Laboratory (DDD Lab), Department of Pharmaceutical Technology, Jadavpur University, Kolkata, 700032, India.

Molecular diversity
|March 9, 2024
PubMed
概括

研究人员确定DB05790是G蛋白结合受体183 (GPR183) 的潜在抑制剂. 这一发现为准与GPR183过度表达相关的疾病提供了新的策略,包括癌症和糖尿病.

关键词:
药品银行 药品银行在 GPR183 中使用.在MM-GBSA中使用.分子对接是分子对接.分子动力学分子动力学在QSAR中使用QSAR.

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Published on: February 21, 2020

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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators07:41

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