患有高血压的人对急性血压的敏感性会因个人水平环境温度下降而增加
Yifan Xu1, Yiqun Han2, Wu Chen1
1BIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering, Center for Environment and Health, Peking University, Beijing, China.
Environment international
|March 9, 2024
概括
患有高血压的老年人经历了显著的血压 (BP) 增加与寒冷的环境温度,与没有高血压的人不同. 管理BP的干预应该及时,特别是在冬季.
科学领域:
- 环境健康 环境健康
- 心血管流行病学心血管流行病学
- 生物气象学生物气象学
背景情况:
- 环境温度与血压 (BP) 有反向关系.
- 高血压可能会放大温度和血压之间的关联.
- 这项研究调查了高血压患者是否更容易因温度下降而升高血压.
研究的目的:
- 为了确定高血压患者对环境温度下降后急性血压升高的易感性.
- 为了比较高血压和非高血压的老年人之间的这种易感性.
- 分析这些关联的时间模式.
主要方法:
- 一项涉及251名老年参与者的研究 (126名高血压患者,125名非高血压患者) 在北京.
- 使用便携式传感器进行持续的个人环境温度 (PET) 监测.
- 线性混合效应和分布式滞后模型将BP (SBP,DBP) 与PET在24小时的滞后时间内关联起来.
主要成果:
- 在高血压患者中,PET降低1°C与SBP增加0.96 mmHg和DBP增加0.28 mmHg相关.
- 非高血压患者的血压增加较小,不那么显著 (0.28 mmHg SBP,0.14 mmHg DBP).
- 患有高血压的个体在PET降低后1小时出现高峰血压升高,降低10小时;在非高血压者中没有显著变化.
结论:
- 环境温度下降会急剧增加血压,影响在10小时内减弱.
- 高血压患者,特别是在冬季,对与温度相关的血压升高的敏感性增加.
- 及时干预对于防止由于暴露于寒冷而导致血压激增至关重要,特别是在高血压人群中.
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