在怀孕期间的生理血压模式,有轻度慢性高血压
Rachel G Sinkey1, Christina T Blanchard1, Ayodeji Sanusi1
1Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, USA.
Pregnancy hypertension
|March 9, 2024
概括
血压轨迹在患有慢性高血压 (CHTN) 的怀孕中有所不同,这些怀孕中患有先兆子 (PEC),与没有先兆子的怀孕中不同,并且与正常血压怀孕相比. 这些独特的模式可能有助于预测PEC风险.
科学领域:
- 产科和妇科 产科和妇科
- 怀孕中的心脏病学
- 怀孕期间的高血压疾病
背景情况:
- 慢性高血压 (CHTN) 影响了大量的怀孕.
- 区分CHTN有和没有孕产前 (PEC) 对于管理至关重要.
- 了解整个妊娠期间血压 (BP) 的变化是识别风险妊娠的关键.
研究的目的:
- 为了比较整个怀孕期间的生理血压 (BP) 变化.
- 评估轻度CHTN患者的血压轨迹,这些患者发展PEC,而不是那些没有.
- 将这些组与正常血压患者进行比较.
主要方法:
- 单子妊娠的回顾性队列研究.
- 包括CHTN患者和正常血压 (NML) 的比较组.
- 使用二次混合模型来估计整个妊娠期间的缩血压 (SBP) 和腹缩血压 (DBP).
主要成果:
- 血压最低点时的中位妊娠年龄 (GA) 不同:NML (SBP 20,DBP 22周),没有PEC的CHTN (SBP 24,DBP 24周) 和带有PEC的CHTN (SBP 21,DBP 21周).
- 在患有CHTN并患有PEC的患者中,不良次要结果更为常见.
- 在这三个组中,BP轨迹显著不同.
结论:
- 怀孕血压轨迹对于具有PEC的CHTN,没有PEC的CHTN和正常血压的患者是不同的.
- 这些不同的血压模式可能有助于评估怀孕期间产前的风险.
- 对高血压动态的进一步研究可以改善怀孕期间高血压疾病的预测和管理.
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