住院治疗是改善高风险患者肺癌查的机会
Ellen M Nielsen1, Jingwen Zhang1, Justin Marsden1
1Department of Medicine, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, United States.
Cancer epidemiology
|March 9, 2024
概括
住院治疗不会增加肺癌查率. 住院患者不太可能完成低剂量计算机断层扫描 (LDCT) 查,这表明在高危人群中错过了早期检测的机会.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 低剂量计算机断层扫描 (LDCT) 的肺癌查可以降低高风险吸烟者的死亡率.
- 在符合条件的成年人中,查率仍然很低.
- 住院治疗为增加查参与提供了潜在的机会.
研究的目的:
- 评估住院和肺癌查完成之间的关联.
- 为医院肺癌查推计划的发展提供信息.
主要方法:
- 使用电子健康记录进行的回顾性队列研究 (2014-2021年).
- 包括55-80岁的有吸烟史的患者,在内科诊所接受治疗.
- 医院住院作为主要暴露和LDCT完成作为结果的分析,使用后勤回归和Cox比例危险模型.
主要成果:
- 1935年21%的高风险吸烟者完成了LDCT查.
- 住院患者 (24%) 的LDCT完成比例高于非住院患者 (18%),p<0.001.
- 在同变量调整 (95% CI 0.680 - 1.149) 后,住院和LDCT完成之间没有关联;然而,住院患者的完成概率较低 (HR 0.747;95% CI 0.611 - 0.914).
结论:
- 只有四分之一的住院高风险患者完成了LDCT查.
- 住院事件与完成LDCT的可能性降低有关.
- 住院代表了一个错过的机会,以推风险较高的个体进行肺癌查.
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