缺乏是COVID-19发展为肺炎的潜在危险因素,需要氧气治疗
Koji Fujita1, Kazuki Ocho2, Tomoka Kadowaki3
1Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; Department of General Internal Medicine and Infectious Diseases, Tsuyama Chuo Hospital, Tsuyama, Japan.
概括
血清缺乏是严重的冠状病毒疾病2019 (COVID-19) 的重要危险因素. 患有缺乏症的患者更有可能经历严重的COVID-19结果,这凸显了营养状况的重要性.
科学领域:
- 营养免疫学 营养免疫学
- 传染性疾病 传染性疾病
- 临床医学 临床医学
背景情况:
- 有限的研究存在于严重的COVID-19的营养风险因素.
- 血清缺乏症被调查为COVID-19严重程度的潜在风险因素.
研究的目的:
- 调查血清水平与COVID-19的严重程度之间的关联.
- 为了确定缺乏是否独立预测严重的COVID-19结果.
主要方法:
- 分析了60名COVID-19患者的队列.
- 患者根据血清含量 (正常或缺乏) 分类.
- 为混因素调整后勤回归检查了缺乏和COVID-19严重程度之间的关联.
主要成果:
- 需要氧气治疗的患者中存在缺乏症.
- 血清缺乏与COVID-19严重程度的增加显著相关 (OR 7.29).
- 在调整了背景因素后,这种关联仍然很重要.
结论:
- 缺乏是严重COVID-19的一个独立风险因素.
- 营养状况,特别是水平,在COVID-19预后中至关重要.
- 建议在外部研究中进一步验证.
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