[胸部瘤学全身治疗的严重并发症]
T Berghmans1, M Brandão1, M Ilzkovitz2
1Clinique d'oncologie thoracique, institut Jules-Bordet, rue Meylemeersch 90, 1070 Bruxelles, Belgique.
Revue des maladies respiratoires
|March 9, 2024
概括
本综述涵盖了系统性癌症治疗的严重并发症,不包括感染. 它强调了新疗法的新出现的毒性,例如瘤学家和全科医生的CAR-T细胞.
科学领域:
- 在瘤学瘤学.
- 内部医学 内部医学
背景情况:
- 主要的胸部癌症,包括肺癌,中皮质瘤和胸部瘤,经常影响具有并发症的老年患者.
- 这些癌症与严重的并发症有关,需要谨慎管理.
研究的目的:
- 介绍胸部恶性瘤的全身治疗引起的严重并发症的临床概述.
- 专注于副作用和与免疫相关的不良事件,不包括感染和呼吸系统紧急情况.
主要方法:
- 文献综述和临床专业知识综合.
- 专注于全身疗法 (化疗,向疗法,免疫疗法) 和它们的相关毒性.
主要成果:
- 系统性治疗可能会导致严重的副作用和与免疫相关的不良事件.
- 像CAR-T细胞,免疫调节剂和抗体-药物联合体这样的创新疗法引入了新的毒性.
结论:
- 一般医生和专家必须意识到系统性癌症治疗的潜在严重并发症.
- 预测和管理与先进疗法相关的新毒性对于患者护理至关重要.
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