在心房的患者中发生全身性心脏病发作
Alexander P Cabulong1, Janet J Tang2, Justin T Teraoka2
1Division of Epidemiology and Biostatistics, University of California, Berkeley, California.
Heart rhythm
|March 10, 2024
概括
心房动 (AF) 显著增加了全身系统性心脏病发作的风险. 这种增加的风险因性别和种族/种族而异,这表明除了中风之外还有更广泛的影响.
科学领域:
- 心血管医学 心血管医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 除了缺血性中风之外,心房动 (AF) 的血栓栓塞并发症尚未得到充分理解.
- 现有的研究主要集中在与AF相关的中风上,而其他系统性并发症尚未被阐明.
研究的目的:
- 描述与心房动 (AF) 相关的全身性心脏病发作的流行病学.
- 通过性别和种族/种族来分析AF相关的全身性心脏病发作之间的相互作用.
主要方法:
- 在加利福尼亚州 (2005-2015) 使用全州健康数据对成年患者 (≥18岁) 的纵向分析.
- 确定了AF和非AF患者中全身性心脏病发作的分布和风险.
- 进行了按性别和种族/民族分层的相互作用分析.
主要成果:
- 与没有AF的患者相比,患有AF的系统性心脏病发作风险增加了45% (HR,1.45).
- 在AF患者中,全身性心脏病发作的年率为2.1%,而非AF患者的年率为0.56%.
- 女性,亚洲人,黑人和西班牙裔AF患者的系统性心脏病发作的相对风险在统计学上显著增加.
结论:
- 心房动 (AF) 与全身心脏病发作的风险增加有关,而不仅仅是大脑.
- 对这些全身性心脏病发作的易感性因性别和种族/种族而异.
- 系统性心脏病发作应该引起对AF的怀疑,突出显示AF预防和抗凝药除了降低中风风险之外,其重要性.
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