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一个特定的炎症抑制纤维细胞亚群,其特征是MHCII表达在人类扩张性心肌病的特征

Xi Fan1, Kai Huang1, Yuming Wu2

  • 1Department of Cardiothoracic Surgery, Huashan Hospital of Fudan University, 12 Wulumuqi Rd, Shanghai, 200040, China.

Molecular and cellular biochemistry
|March 11, 2024
PubMed
概括

研究人员发现了一个新的纤维细胞亚型,抗原呈现纤维细胞 (apFBs),在扩张性心肌病 (DCM). 这些apFBs表达MHCII基因并有助于抑制炎症,为心力衰竭提供潜在的治疗点.

关键词:
扩展性心肌病变异症 扩展性心肌病变异症纤维细胞异质性的异质性炎症 炎症是一种炎症.单细胞RNA测序的一个细胞.

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