与腹部儿科生殖细胞瘤相关的不寻常的成像发现
Marie-Helene Gagnon1, Paul-Robert Derenoncourt2, Sampanna Rayamahi2
1Department of Radiology & Imaging Sciences, Emory University and Children's Healthcare of Atlanta, 1405 Clifton Road NE, Atlanta, GA, 30322, USA. marieheleneg8@gmail.com.
儿童腹部生殖细胞瘤可能呈现异常. 本综述强调了非典型的成像和临床特征,包括罕见的并发症和综合征,以帮助诊断.
科学领域:
- 儿科瘤学 儿科瘤学
- 诊断成像 诊断成像 诊断成像
- 医学遗传学 医学遗传学
背景情况:
- 胚胎细胞瘤 (GCTs) 起源于阴道或外阴道部位的胚胎细胞.
- 额外体GCT通常发生在中线位置,如大脑,中体,体或骨盆.
- 虽然经常通过特征性成像和标记物来诊断,但GCTs可能会表现出不寻常的表现.
研究的目的:
- 为了说明小时候腹部生殖细胞瘤的非典型成像和临床表现.
- 审查不寻常的原发性瘤表现,局部并发症和转移性疾病模式.
- 为了突出与这些瘤相关的罕见内分泌和副瘤综合征.
主要方法:
- 文献综述,重点关注儿科患者腹部生殖细胞瘤的非典型表现.
- 对成像发现,临床综合征和并发症的分析.
- 不寻常的特征的分类包括多焦点原发性,卵巢扭曲,破裂的皮质,烧毁的瘤,生长的瘤综合征,膜质,早熟青春期,甲状腺功能障碍和副发性脑炎.
主要成果:
- 腹部生殖细胞瘤可以表现为多焦点初级,卵巢扭曲或破裂皮质囊.
- 转移性疾病可能呈现为烧毁的原发性瘤,生长的瘤综合征或膜质症.
- 内分泌干扰 (过早的青春期,甲状腺功能障碍) 和抗体介导综合征 (抗NMDAR脑炎) 是罕见但重要的关联.
结论:
- 放射科医生和临床医生应该意识到儿童腹部生殖细胞瘤的多样性和不典型表现.
- 识别这些不寻常的特征对于准确诊断和及时管理至关重要.
- 本综述提供了对罕见症状的全面概述,以提高诊断准确度.
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