相关实验视频

Updated: Jul 1, 2025

Establishing Single-Cell Based Co-Cultures in a Deterministic Manner with a Microfluidic Chip
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Establishing Single-Cell Based Co-Cultures in a Deterministic Manner with a Microfluidic Chip

Published on: September 27, 2019

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简化稳定的CHO细胞系的产生,具有高的单克隆性概率,通过使用微流体分配作为光激活细胞分类的替代方案

Lina Chakrabarti1, James Savery2, John Patrick Mpindi3

  • 1Cell Culture & Fermentation Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, USA.

Biotechnology progress
|March 11, 2024
PubMed
概括

微流体细胞分剂提供了一个经济高效,用户友好的替代方案,以光激活细胞分类 (FACS) 单细胞克隆在生物制药细胞系开发 (CLD). 这项技术实现了高的单克隆性率,简化了CLD并降低了成本.

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相关概念视频

Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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