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Agnes Sze Yin Leung1, Elizabeth Huiwen Tham2, Punchama Pacharn3
1Department of Paediatrics, Prince of Wales Hospital, Hong Kong Hub of Paediatric Excellence, The Chinese University of Hong Kong, Shatin, Hong Kong.
Allergy
|March 11, 2024
概括
亚洲儿童的过敏反应经常是由食物引发的,过敏原因国家而异. 上腺素治疗和设备处方的效果不足于最佳水平,这凸显了亚太地区改善过敏反应护理的需要.
科学领域:
- 儿科过敏和免疫学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 亚洲的过敏反应流行病学和管理数据有限.
- 亚太过敏症研究网络 (APRA) 建立了一个注册表来弥补这一缺口.
研究的目的:
- 评估亚太地区儿科过敏反应的触发因素,症状,严重程度和治疗方法.
- 为了比较不同亚洲国家/城市的过敏反应特征.
主要方法:
- 从区域儿科过敏反应登记处采用标准化协议进行前性数据收集.
- 包括亚洲四个地区 (泰国,新加坡,香港,青岛) 呈现过敏反应的儿科患者 (<18岁).
主要成果:
- 在2019-2022年期间,689名患者中发现了721次过敏反应发作.
- 食物是最常见的触发因素 (62%),具体的过敏原因年龄和位置而异 (例如,幼儿的蛋/牛奶,HK/新加坡的坚果,曼谷的小麦,老年儿童的贝类).
- 上腺素在60%的病例中被给予,在医院前使用率低 (9%);上腺素装置的处方有显著的变化 (0-82%).
结论:
- 食物是亚洲儿科过敏症的主要触发因素,但特定的过敏原在地理上是多样化的.
- 上腺素治疗的不足使用和低于最佳的设备处方表明需要加强过敏反应管理策略.
- 该APRA注册突出了改善亚太地区过敏反应护理和研究的关键领域.
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