胃癌老年患者的脆弱性和不良结果之间的关系:一个范围审查
Zheng-Ke-Ke Tan1, Wen-Zhen Tang1, Kui Jia2
1Departments ofNursing.
Annals of medicine and surgery (2012)
|March 11, 2024
概括
手术前的脆弱性显著增加了老年胃癌患者的不良结果. 早期识别和管理脆弱性对于改善患者治疗结果和生活质量至关重要.
科学领域:
- 老年医学 老年医学
- 手术瘤学手术瘤学
- 公共卫生 公共卫生
背景情况:
- 虚弱是老年患者手术前评估的一个关键因素.
- 以前的研究将虚弱与胃癌 (GC) 患者的并发症和死亡率联系在一起.
- 不断发展的以患者为中心的方法需要更广泛地了解脆弱对各种健康结果的影响.
研究的目的:
- 探索患有胃癌的老年患者的脆弱性和各种不良健康相关结果之间的关系.
- 综合现有文献中关于脆弱性评估及其对GC术后结果的影响的证据.
- 提供有关老年GC患者脆弱性的当前研究格局的全面概述.
主要方法:
- 在多个数据库 (PubMed,Embase,Web of Science等) 进行了系统的文献搜索. 在2023年8月之前.
- 关键词包括"脆弱"和"胃癌" (以及同义词).
- 包括的研究是观察性或队列研究,评估术后结果;方法质量是使用标准化工具来评估的.
主要成果:
- 十五项研究 (4个横截面,8个回顾性队列,3个前性队列) 符合纳入标准,具有高的整体文献质量.
- 确定并分类了十种脆弱性评估工具.
- 老年GC患者的虚弱与术后并发症,死亡率,住院,再入院,生活质量下降,非家庭出院和ICU入院的增加有关.
结论:
- 在接受胃癌治疗的老年患者中,高水平的手术前脆弱性增加了不良结果的风险.
- 预计脆弱性评估将成为老年GC患者临床评估的组成部分.
- 实施精确的风险分层和积极的脆弱性管理对于减轻不良治疗结果至关重要.
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