基于碳点的碳纳米粒子作为强大的抗微生物,抗病毒和抗癌剂
Narmin Hamaamin Hussen1, Aso Hameed Hasan2,3, Yar Muhammed FaqiKhedr1
1Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, University of Sulaimani, Sulaimani 46001, Iraq.
ACS omega
|March 11, 2024
概括
碳点 (C-dots) 作为新型抗微生物和抗癌剂具有前途,为面对日益增长的微生物耐药性的传统药物提供低毒性替代品. 本综述探讨了它们的结构,合成和治疗应用.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 生物医学工程 生物医学工程
背景情况:
- 全球因传染病和癌症死亡率上升.
- 增加微生物对常规抗生素的耐药性.
- 需要具有低毒性和高疗效的新型治疗剂.
研究的目的:
- 审查碳点 (C点) 的结构,分类和合成.
- 探索C点对细菌,真菌和病毒病原体的抗菌应用.
- 为了研究C点的抗癌活动,以治疗开发.
主要方法:
- 关于碳点合成和表征的文献综述.
- 关于C点抗微生物药物在体外和体内疗效的研究分析.
- 对C点抗癌机制和应用的研究评估.
主要成果:
- C点具有低毒性,良好的分散性和生物相容性.
- "C"点显示出显著的抗菌,抗真菌和抗病毒特性.
- C点显示出对各种癌症细胞系有前途的抗癌活性.
结论:
- 碳点是多功能纳米材料,在抗微生物和抗癌疗法中具有重大潜力.
- 进一步研究C点功能化和有针对性的交付可以提高其临床适用性.
- 对于开发下一代治疗剂来说,C点是一个有前途的途径.
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