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Updated: Jul 1, 2025

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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作为抗凝固剂的新型基于triazole的人类因子XIIa的强效抑制剂

Ma'Lik D Woodland1, Anthony Thompson2, Amanda Lipford2

  • 1Division of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, Louisiana 70125, United States.

ACS omega
|March 11, 2024
PubMed
概括

新型三醇化合物8和22有效抑制XIIa因子 (FXIIa),这是血液凝固中的关键酶. 这些强效和选择性抑制剂为治疗血栓栓塞性疾病的更安全的抗凝固疗法提供了一个有希望的新途径.

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