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状体内切割减少了复发:对608个状体的可用文献进行了分析性研究

Nathan G Lawera¹, Jules Madzia¹, Liann C Casey¹

¹From Division of Pediatric Plastic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Plastic and reconstructive surgery. Global open

|March 11, 2024

概括

体内伤口切除 (KILE) 的复发率为13%,明显低于单独的完整切除. 这一元分析表明,KILE是一种有前途的技术,用于预防 keloid 复发.

科学领域:

皮肤病学皮肤病学
手术瘤学手术瘤学
整形外科整形外科整形外科

背景情况:

仅仅经过手术切除后,状体的复发率很高,通常在45%至100%之间.
目前的胆固醇治疗缺乏广泛接受的指导方针,导致各种辅助疗法.
尽管进行了一些干预措施,但状细胞的复发仍然是一个重大的临床挑战.

研究的目的:

评估 keloid 内伤切除 (KILE) 在预防 keloid 复发方面的有效性.
进行关于KILE.现有文献的元分析.
确定KILE在降低 keloid 复发率中的作用.

主要方法:

使用PubMed,Scopus和Web of Science数据库进行了全面的文献审查.
两个独立审查员评估了研究资格.
进行了比例的元分析,以计算用KILE治疗的 keloids 的聚合复发率.

主要成果:

分析了22项涉及608个体的研究.
在KILE后的综合复发率为13% (95%CI,9%-16%).
与KILE一起使用的辅助疗法对整体复发率没有显著影响.

结论:

状体内伤口切除 (KILE) 在预防状体复发方面表现出有效性,综合率为13%.
与单独的完全切除相比,KILE可以显著减少复发.
这一元分析支持KILE作为 keloid 管理的有前途的治疗选择.

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