多重狭窄和动脉动脉瘤对动脉疾病的影响:心血管研究
Mohammed Nasir Uddin1, K E Hoque2, M M Billah2
1Department of Information and Communication Technology (ICT), Bangladesh University of Professionals (BUP), Dhaka-1216, Bangladesh.
Heliyon
|March 11, 2024
概括
动脉中的连续狭窄症会比动脉瘤引起更多的异常血流,这表明动脉样硬化的严重程度更大. 这项研究分析了患病动脉中的血流动力学,以评估心血管疾病风险.
科学领域:
- 生物医学工程 生物医学工程
- 流体动力学 流体动力学
- 心血管科学 心血管科学
背景情况:
- 动脉样硬化包括动脉收窄 (缩小) 和气球 (动脉动脉瘤),影响血液流动.
- 了解连续狭窄和动脉瘤的综合影响对于疾病严重程度的评估至关重要.
研究的目的:
- 为了比较分析连续狭窄和动脉动脉瘤的血液流动效应.
- 通过检查这些条件下的血液行为来评估动脉样硬化的严重程度.
主要方法:
- 利用有限元法解决连续性,动量和奥尔德罗伊德-B部分微分方程.
- 模拟了牛顿式和非牛顿式的血流,用于粘弹性分析.
- 调查了四起同时发生连续狭窄和动脉瘤的病例.
主要成果:
- 连续狭窄症表现出比动脉瘤更大的异常血流效应,这意味着动脉样硬化的严重程度更高.
- 在狭窄中心观察到更高的血液速度和壁剪应力 (WSS),较低的动脉壁正常梯度.
- 动脉瘤模型显示速度,WSS和动脉壁正常梯度的结果相反.
- 增加的雷诺兹数在狭窄和动脉瘤模型中显著影响了血液流动.
结论:
- 连续性狭窄症比动脉瘤更重要地表明动脉样硬化的严重程度.
- 血流特征如速度,压力和WSS在狭窄和动脉瘤区域之间显著不同.
- 这些发现可以帮助医学专家评估心血管疾病的严重程度.
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