对比内镜逆行胆瘤学 (ERCP) 的镇静方案:一个回顾性研究
1Department of Cardiopulmonary Rehabilitation, Shandong Provincial Third Hospital, No.12, Wuyingshan Middle Road, Jinan, Shandong, 250000, China.
Heliyon
|March 11, 2024
概括
普罗波和德克斯梅托米丁 (Pro-Dex) 镇静方案为内逆向胆瘤学术 (ERCP) 程序提供了更好的质量和更快的恢复. 虽然Pro-Dex显示出优势,但所有四种镇静方法都有类似的ERCP相关不良事件率.
科学领域:
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
- 临床药理学 临床药理学
背景情况:
- 透镜逆行胆瘤胆瘤学 (ERCP) 是一个重要的诊断和治疗程序.
- 在ERCP期间,有效的镇静对于患者的舒适性和程序的成功至关重要.
- 常见的镇静方案包括单独使用普罗波,普罗波和德克斯梅托米丁 (Pro-Dex),胺和普罗波 (Keto-Fol),以及普罗波和米达佐 (Pro-Mid).
研究的目的:
- 为了追溯比较ERCP期间使用的四种不同的镇静方案的安全性和有效性.
- 评估协议之间的患者康复,镇静水平和并发症率的差异.
主要方法:
- 在2018年至2021年期间,对600名接受ERCP的患者进行了回顾性分析.
- 根据内镜医生的偏好,患者接受了四种镇静方案之一.
- 收集的数据包括血液动力学参数,镇静水平 (兰赛镇静量表),恢复时间和并发症.
主要成果:
- 普罗德克斯 (Pro-Dex) 组表现出明显较低的普罗波福尔剂量和更快的恢复时间.
- 在四组中没有观察到呼吸抑郁,低血压或心衰竭的显著差异.
- 更高的身体质量指数 (BMI) 与更不利的结果的趋势有关.
结论:
- 与其他方案相比,Pro-Dex协议显示出优越的镇静质量和更快的恢复速度.
- 在研究的镇静方案中,没有发现与ERCP相关的不良事件的显著变化.
- 这些发现支持基于患者和内镜师因素的ERCP镇静协议的知情选择.
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