一项基于实验室的横截面研究,研究了Helicobacter pylori感染和糖尿病
Mehrdad Haghighi1, Mehdi Goudarzi2, Abdolreza Babamahmoodi3
1Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Caspian journal of internal medicine
|March 11, 2024
概括
慢性Helicobacter pylori感染可能与2型糖尿病患者的HbA1c水平较高有关. 建议对高风险人群进行早期的H. pylori检测和血糖监测.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
背景情况:
- 关于2型糖尿病 (DMT2) 与慢性Helicobacter pylori (H. pylori) 感染之间的联系存在不一致的发现.
- 这项研究旨在调查H. pylori感染与DMT2之间的潜在关联.
研究的目的:
- 为了检查H. pylori感染在患有HbA1c水平升高的患者中的流行率.
- 为了确定H. pylori感染是否与DMT2.2有关.
主要方法:
- 在德黑兰实验室接受HbA1c测试的个体中测量了H. pylori便抗原 (HpSA).
- 总共有2025名HbA1c水平高于6.5%的患者被纳入分析.
主要成果:
- 超过一半 (52.84%) 的患有HbA1c水平升高的患者检测出HPSA阳性.
- 与非糖尿病组 (37.36%) 相比,糖尿病 (DM) 组 (52.84%) 的HpSA阳性值明显高于非DM组 (37.36%).
- HpSA阳性显示出与年龄 (P=0.034) 有显著相关性,但与性别 (P=0.274) 没有显著相关性.
结论:
- 长期的H. pylori感染可能与HbA1c水平升高有显著关联.
- 查H. pylori感染和定期监测血糖和HbA1c对于高风险个人来说是建议的,以帮助预防DMT2.
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