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Updated: Jul 1, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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FOXK1的O-GlcNAcylation调节了E2F通路,并促进了瘤发生

Louis Masclef1, Oumaima Ahmed1, Nicholas Iannantuono2

  • 1Centre de recherche de l'Hôpital Maisonneuve-Rosemont, CIUSSS de l'Est-de-l'Île de Montréal, 5415 boulevard de l'Assomption, Montréal, QC, H1T 2M4, Canada.

bioRxiv : the preprint server for biology
|March 11, 2024
PubMed
概括

叉头盒K1 (FOXK1) 通过调节E2F通路,促进细胞增殖和瘤开始. FOXK1的O-GlcNAcylation对于其致癌功能和与BAP1的相互作用至关重要,影响细胞周期控制.

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