人类calpain-3及其结构可塑性:在结合titin上将同质合体分解成二元体

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Updated: Jul 1, 2025

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

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Qilu Ye1, Amy Henrickson2, Borries Demeler2

  • 1Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, K7L 3N6, Canada.

bioRxiv : the preprint server for biology
|March 11, 2024
PubMed
概括

卡尔帕因-3,对于肌肉修复至关重要,形成不活跃的六合体,在结合丁后分离为活跃的二合体. 这种结构洞察力有助于理解四肢腰带肌肉发育不良.

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