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Updated: Jul 1, 2025

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
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在不同的盐状况下,α-Synuclein的分离和聚合相位不同

Rebecca Sternke-Hoffmann1, Xun Sun1, Andreas Menzel2

  • 1Department of Biology and Chemistry, Paul Scherrer Institute, Forschungsstrasse 111, 5232 Villigen PSI, Switzerland.

bioRxiv : the preprint server for biology
|March 11, 2024
PubMed
概括

帕金森病的蛋白质α-synuclein (αSyn) 聚合和液体-液体相分离 (LLPS) 显示出明显的盐分依赖. 滴滴阶段可以抑制αSyn聚合,提供新的治疗见解.

关键词:
聚合是一种聚合.生物分子凝结物 生物分子凝结物本质上有障碍的蛋白质.液-液相分离器 液相分离器分子动力学分子动力学

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