在合的库拉莫托振荡器网络中对同步和网络重组产生神经调节效应
bioRxiv : the preprint server for biology
|March 11, 2024
概括
大脑神经调节改变了网络动态. 2型网络同步并将频率映射到相位,与1型网络不同,特别是可塑性. 这揭示了不同的网络重组机制.
科学领域:
- 计算神经科学是一种神经科学.
- 系统神经科学 系统神经科学
背景情况:
- 神经调节过程显著影响神经信号处理和网络重组.
- 乙胆 (ACh) 水平可以改变神经振荡器的相响应曲线 (PRC),使其在1型和2型动态之间转移.
研究的目的:
- 为了研究如何改变阶段反应曲线形状 (类型1到类型2),受ACH水平的影响,影响神经网络重组.
- 探索神经调节和活动依赖可塑性之间的相互作用,改变网络动态.
- 为了比较1型和2型振荡器模型中的网络重组模式.
主要方法:
- 使用合的非相同的库拉莫托振荡器来建模神经网络.
- 模拟具有不同阶段响应曲线形状的网络 (类型 1 与类型 1 相比). 类型2) 通过乙胆调节.
- 将活动依赖的可塑性纳入网络模型.
主要成果:
- 没有可塑性的1型网络表现出异步动态,在高频振荡器中相位演变更快.
- 2型网络同步,显示高频振荡器相对于低频振荡器的相位领先一致.
- 在2型网络中,这种频率相位关系在存在可塑性时建立结构/频率映射,而这种可塑性在1型网络中是不存在的.
结论:
- 类型2网络在存在可塑性时显示出强大的结构/频率映射.
- 2型网络中明显的同步和相锁定行为在1型网络中没有复制,即使具有可塑性.
更多相关视频
08:28Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays
Published on: April 26, 2018
6.0K
04:44Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
Published on: July 21, 2021
4.2K
相关概念视频
Propagation of Action Potentials
5.7K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
5.7K
Excitatory and Inhibitory Effects of Neurotransmitters
10.0K
When an action potential reaches the presynaptic axon terminal, it releases neurotransmitters from the neuron into the synaptic cleft at a chemical synapse. The released neurotransmitter can be excitatory or inhibitory. The critical criteria commonly used to determine whether a molecule is a neurotransmitter at a chemical synapse are the molecule's presence in the presynaptic neuron. Second, its release is in response to strong presynaptic depolarization. And lastly, the presence of...
10.0K
Oscillations about an Equilibrium Position
5.4K
Stability is an important concept in oscillation. If an equilibrium point is stable, a slight disturbance of an object that is initially at the stable equilibrium point will cause the object to oscillate around that point. For an unstable equilibrium point, if the object is disturbed slightly, it will not return to the equilibrium point. There are three conditions for equilibrium points—stable, unstable, and half-stable. A half-stable equilibrium point is also unstable, but is named so...
5.4K
Damped Oscillations
5.7K
In the real world, oscillations seldom follow true simple harmonic motion. A system that continues its motion indefinitely without losing its amplitude is termed undamped. However, friction of some sort usually dampens the motion, so it fades away or needs more force to continue. For example, a guitar string stops oscillating a few seconds after being plucked. Similarly, one must continually push a swing to keep a child swinging on a playground.
Although friction and other non-conservative...
Although friction and other non-conservative...
5.7K
Oscillations In An LC Circuit
2.3K
An idealized LC circuit of zero resistance can oscillate without any source of emf by shifting the energy stored in the circuit between the electric and magnetic fields. In such an LC circuit, if the capacitor contains a charge q before the switch is closed, then all the energy of the circuit is initially stored in the electric field of the capacitor. This energy is given by
2.3K
Muscle Stimulation Frequency
2.2K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
2.2K
