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Updated: Jul 1, 2025

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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整体粘附GPCR的结构分析和构造动力学揭示了细胞外和膜外域之间的相互作用

Szymon P Kordon, Kristina Cechova, Sumit J Bandekar

    bioRxiv : the preprint server for biology
    |March 11, 2024
    PubMed
    概括

    粘附G蛋白结合受体 (aGPCRs) 使用它们的大细胞外区域 (ECR) 来信号. 这项研究揭示了ECR内的GAIN域如何连接到跨膜域,影响aGPCR激活.

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