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Updated: Jul 1, 2025

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring

Published on: June 23, 2015

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与瘤结裂相关的FBW7调解了ADPKD中瘤依赖性功能下降

Maulin Mukeshchandra Patel, Vasileios Gerakopoulos, Eleni Petsouki

    bioRxiv : the preprint server for biology
    |March 11, 2024
    PubMed
    概括

    在多囊病 (PKD) 中,FBW7 E3 泛素酶重编程影响功能. 在ADPKD脏中FBW7的积累将囊的生长与脏衰退联系在一起,与纤维化占主导地位的NPHP不同.

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