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Updated: Jun 11, 2026

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
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MTSS1下调对扩展性心肌病的性别特异性影响

Dongwook Choe1,2, Megan Burke1,2, Jeffrey A Brandimarto1,2

  • 1Division of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medline, Philadelphia, PA, USA.

medRxiv : the preprint server for health sciences
|March 11, 2024
PubMed
概括

在MTSS1 (转移抑制剂1) 的遗传变异保护免受扩张性心肌病,与性别的影响不同. 较低的MTSS1表达在雌性小鼠中部分挽救了心脏功能,并且与女性的心脏特征有关.

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