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在患者中,单碳代谢与酸诱导的肝功能障碍之间的关联

Jingwei Zhu1, Zhe Wang1, Xiaotong Sun1

  • 1Department of Clinical Laboratory, Qingdao University Medical College Affiliated Yantai Yuhuangding Hospital, Yantai, China.

Frontiers in pharmacology
|March 11, 2024
PubMed
概括

基因变异的MTHFR (甲基基酸减少酶) 和高水平的同类氨酸 (Hcy) 与酸 (VPA) 诱导的儿科患者的肝损伤有关. 这些因素可能表明个体对VPA肝毒性的敏感性.

关键词:
在MTHFR A1298C中使用.在MTHFR C677T中,它是最常见的.瓦尔酸是一种酸.同型半氨酸同型半氨酸肝脏功能障碍 肝脏功能障碍一个碳代谢的一个碳代谢.氧化应激是一种氧化应激.

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