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三甘油糖指数与结直肠多体之间的关联:一项追溯的横截面研究

Ya-Jie Teng¹, Ying-Xue Yang¹, Jing-Jing Yang¹

¹Department of Gastroenterology, The First People's Hospital of Kunshan, Suzhou 215300, Jiangsu Province, China.

World journal of gastrointestinal endoscopy

|March 11, 2024

概括

甘油三糖 (TyG) 指数显示,中国成年人与结直肠多瘤 (CPs) 有曲线联系. 该指数可能有助于制定结肠镜查策略,以预防结肠直肠癌.

科学领域:

胃肠病学胃肠病学
代谢健康代谢健康
预防癌症预防癌症

背景情况:

结肠直肠多 (CPs) 是结肠直肠癌 (CRC) 的前体.
甘油三糖 (TyG) 指数是代谢健康和胰岛素耐药性的标志物.
以前的研究已经将TyG指数与胃肠道癌症联系起来.

研究的目的:

调查TyG指数与CP的流行率之间的关联.
探索 TyG 指数在 CRC 查策略中的潜力.

主要方法:

对2537名接受结肠镜检查的人进行了回顾性横截面研究.
后勤回归分析以评估TyG指数和CP之间的关联.
TyG指数计算为Ln [三甘油 (mg/dL) ×葡萄糖 (mg/dL) /2] .

主要成果:

在TyG指数和CP之间发现了显著的曲线关联 (切断点2.31).
赔率比率为1.70 (1.40,2.06) 表明在截止点之前存在显著的关联 (P < 0.0001).
在截止点 (OR 0.57;P = 0.1521) 之后没有观察到任何显著的关联.

结论:

TyG指数显示了中国人口中CP的曲线关联.
TyG指数可能是制定有针对性的结肠镜查策略的有用工具.
进一步的研究可以探索TyG指数在早期CRC检测和预防中的作用.

关键词:

结肠直肠癌是一种癌症.结肠直肠的多体横截面研究横截面研究胰岛素耐药性胰岛素耐药性是一种三糖-葡萄糖指数是什么意思

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