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左心室重塑与肥胖儿童的脂质概况之间的关联:一项观察性研究

Ying Tang¹, Guang-Bin Yang², Jun Chen¹

¹Department of Ultrasound, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Frontiers in pediatrics

|March 11, 2024

概括

儿童肥胖导致儿童的左心室重塑. 较低的高密度脂蛋白胆固醇 (HDL-C) 与更严重的左心室缩有关,这表明一个集中式的模式.

科学领域:

心脏病学心脏病学
儿科儿科儿科
代谢障碍代谢障碍代谢障碍

背景情况:

儿童肥胖是一个日益严重的公共卫生问题.
肥胖会导致左心室重塑和成人心血管并发症.
了解儿童肥胖和心脏变化之间的联系对于预防至关重要.

研究的目的:

为了研究左心室重塑与肥胖儿童的血脂概况之间的关系.
确定与儿科肥胖症中心脏结构变化相关的特定脂质标记物.
为预防肥胖年轻人心血管疾病提供有针对性的干预信息.

主要方法:

140名肥胖儿童和40名非肥胖儿童的比较研究.
心声造影以评估左心室的结构和功能.
多重线性回归和相关性分析,以评估脂质水平对心脏参数的影响.

主要成果:

肥胖儿童的BMI,体脂,血压和不良脂质概况 (较低的HDL-C) 增加.
在左心室质量和BMI/SBP之间,以及在LVMI/RWT和HDL-C之间发现了显著的相关性.
集中性缩与最低的HDL-C水平有关.

结论:

肥胖儿童表现出左心室重塑.
左心室配置与血清HDL-C水平密切相关.
降低的HDL-C有助于更严重的左心室缩,特别是同心的模式.

关键词:

心脏功能是指心脏功能.儿童肥胖儿童肥胖儿童肥胖脱脂血症是什么脱脂血症超声心电图 (Echocardiography) 是一种心声回声仪.这里是心室室.

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